Donato Rigante Selected Research

Interleukin 1 Receptor Antagonist Protein (Anakinra)

8/2021	Early introduction of anakinra improves acute pericarditis and prevents tamponade in Staphylococcal sepsis.
1/2020	The Presence of Uveitis Is Associated with a Sustained Response to the Interleukin (IL)-1 Inhibitors Anakinra and Canakinumab in Behçet's Disease.
1/2020	New Potential Weapons for Refractory Scleritis in the Era of Targeted Therapy.
1/2020	Comparison of Early vs. Delayed Anakinra Treatment in Patients With Adult Onset Still's Disease and Effect on Clinical and Laboratory Outcomes.
4/2019	Unveiling the Efficacy, Safety, and Tolerability of Anti-Interleukin-1 Treatment in Monogenic and Multifactorial Autoinflammatory Diseases.
1/2019	Long-Term Retention Rate of Anakinra in Adult Onset Still's Disease and Predictive Factors for Treatment Response.
1/2019	Anakinra Drug Retention Rate and Predictive Factors of Long-Term Response in Systemic Juvenile Idiopathic Arthritis and Adult Onset Still Disease.
7/2018	Resolution of femoral metaphyseal dysplasia in CINCA syndrome after long-term treatment with interleukin-1 blockade.
10/2017	The emerging role of interleukin (IL)-1 in the pathogenesis and treatment of inflammatory and degenerative eye diseases.
7/2017	Efficacy and safety of anakinra in tumor necrosis factor receptor-associated periodic syndrome (TRAPS) complicated by severe renal failure: a report after long-term follow-up and review of the literature.

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Donato Rigante Research Topics

Disease

23	Fever (Fevers) 10/2021 - 11/2006
18	Cryopyrin-Associated Periodic Syndromes 01/2021 - 08/2010
18	Inflammation (Inflammations) 01/2020 - 11/2006
16	Uveitis 02/2020 - 02/2012
14	Familial Mediterranean Fever (Periodic Disease) 01/2022 - 11/2005
14	Infections 01/2022 - 04/2003
14	autosomal dominant familial Periodic fever 01/2021 - 08/2011
13	Mevalonate Kinase Deficiency 01/2021 - 11/2006
10	Mucocutaneous Lymph Node Syndrome (Kawasaki Disease) 11/2021 - 02/2010
10	Juvenile Arthritis (Juvenile Idiopathic Arthritis) 10/2021 - 02/2010
7	Acquired Immunodeficiency Syndrome (AIDS) 10/2021 - 01/2015
7	Necrosis 07/2020 - 05/2013
6	Purpura 05/2020 - 05/2010
6	Arthritis (Polyarthritis) 10/2019 - 05/2010
4	Pericarditis 08/2021 - 07/2012
4	Autoimmune Diseases (Autoimmune Disease) 05/2021 - 12/2014
4	Adult-Onset Still's Disease 01/2020 - 05/2016
4	Behcet Syndrome (Behcet's Syndrome) 01/2020 - 06/2012
4	Amyloidosis 01/2020 - 11/2005
4	Vasculitis (Vasculitides) 01/2018 - 10/2013
3	Inborn Genetic Diseases (Disease, Hereditary) 10/2021 - 01/2013
3	Proteinuria 01/2021 - 07/2015
3	Blau syndrome 01/2021 - 01/2013
3	Systemic Lupus Erythematosus (Libman-Sacks Disease) 05/2019 - 07/2015
3	Rheumatoid Arthritis 05/2019 - 01/2015
3	Gout 05/2016 - 01/2015
3	Pharyngitis (Sore Throat) 01/2015 - 05/2013
2	Serositis 01/2021 - 01/2019
2	Neoplasms (Cancer) 01/2021 - 10/2019
2	Urticaria (Hives) 01/2021 - 07/2015
2	Skin Manifestations 01/2021 - 12/2017
2	Axial Spondyloarthritis 01/2020 - 07/2018
2	Rheumatic Diseases (Rheumatism) 01/2020 - 03/2018
2	Abdominal Pain (Pain, Abdominal) 01/2020 - 05/2010
2	Lymphadenopathy 01/2020 - 01/2015
2	Scleritis (Episcleritis) 01/2020 - 10/2017
2	Chickenpox 01/2020 - 06/2008
2	Streptococcal Infections (Streptococcal Infection) 10/2019 - 01/2018
2	Systemic Scleroderma (Systemic Sclerosis) 05/2019 - 03/2015
2	Panuveitis 02/2019 - 06/2015
2	Exanthema (Rash) 01/2019 - 01/2007
2	Retinal Vasculitis 10/2018 - 07/2017
2	Ankylosing Spondylitis 07/2018 - 05/2015

Drug/Important Bio-Agent (IBA)

22	Interleukin 1 Receptor Antagonist Protein (Anakinra)FDA Link 08/2021 - 11/2006
17	Interleukin-1 (Interleukin 1)IBA 01/2021 - 12/2011
14	InterleukinsIBA 01/2021 - 05/2013
14	CytokinesIBA 08/2020 - 01/2013
13	InflammasomesIBA 01/2022 - 01/2013
12	Biological ProductsIBA 10/2021 - 03/2006
11	Adrenal Cortex Hormones (Corticosteroids)IBA 10/2019 - 01/2007
10	AutoantibodiesIBA 05/2021 - 08/2009
10	Colchicine FDA LinkGeneric 01/2021 - 11/2006
10	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 01/2021 - 01/2014
10	Intravenous Immunoglobulins (IVIG)FDA Link 08/2016 - 06/2008
9	canakinumab FDA Link 01/2020 - 04/2015
8	Interleukin-1 Receptors (Interleukin 1 Receptor)IBA 01/2021 - 11/2006
8	Pharmaceutical PreparationsIBA 01/2020 - 01/2003
6	C-Reactive ProteinIBA 11/2021 - 09/2012
6	SteroidsIBA 01/2021 - 03/2004
6	Proteins (Proteins, Gene)FDA Link 08/2020 - 01/2013
6	AntibodiesIBA 07/2020 - 12/2012
5	EnzymesIBA 10/2021 - 12/2012
5	Immunoglobulins (Immunoglobulin)IBA 01/2021 - 02/2010
5	Monoclonal AntibodiesIBA 01/2021 - 06/2015
4	Vitamin D FDA LinkGeneric 10/2020 - 06/2014
4	Tumor Necrosis Factor InhibitorsIBA 01/2020 - 05/2013
4	Infliximab (Remicade)FDA Link 02/2019 - 06/2015
4	Adalimumab (Humira)FDA Link 02/2019 - 01/2018
4	Immunoglobulin A (IgA)IBA 10/2018 - 11/2005
4	Etanercept (Enbrel)FDA Link 12/2016 - 11/2006
3	GlycosaminoglycansIBA 10/2021 - 01/2002
3	Anti-Bacterial Agents (Antibiotics)IBA 08/2021 - 09/2019
3	AutoantigensIBA 05/2021 - 07/2015
3	Transcription Factors (Transcription Factor)IBA 08/2020 - 04/2017
3	Antirheumatic Agents (DMARD)IBA 02/2020 - 01/2018
3	VaccinesIBA 01/2020 - 12/2017
3	tocilizumab (atlizumab)FDA Link 01/2020 - 05/2016
3	Ferritins (Ferritin)IBA 10/2019 - 02/2007
3	Immunosuppressive Agents (Immunosuppressants)IBA 10/2019 - 07/2012
3	AA amyloidosisIBA 01/2019 - 07/2015
3	Complement System Proteins (Complement)IBA 01/2018 - 03/2012
3	Antigen-Antibody Complex (Immune Complex)IBA 01/2018 - 01/2015
3	Aspirin (Acetylsalicylic Acid)FDA LinkGeneric 01/2017 - 02/2010
3	Immunoglobulin D (IgD)IBA 04/2016 - 11/2006
2	Serum Amyloid A Protein (Serum Amyloid A)IBA 01/2021 - 07/2015
2	Acute-Phase Proteins (Acute-Phase Protein)IBA 08/2020 - 05/2010
2	UbiquitinIBA 08/2020 - 01/2018
2	Proteasome Endopeptidase Complex (Proteasome)IBA 08/2020 - 01/2018
2	secukinumabIBA 01/2020 - 07/2018
2	Attenuated VaccinesIBA 01/2020 - 03/2018
2	Abatacept (Orencia)FDA Link 01/2020 - 05/2016
2	Rituximab (Mabthera)FDA Link 01/2020 - 10/2015
2	Transaminases (Aminotransferases)IBA 01/2020 - 01/2017
2	golimumab FDA Link 07/2019 - 01/2019
2	Membrane Proteins (Integral Membrane Proteins)IBA 02/2019 - 06/2018
2	Amyloid (Amyloid Fibrils)IBA 01/2019 - 07/2015

Therapy/Procedure

27	Therapeutics 08/2021 - 01/2003
4	Biological Therapy 01/2020 - 05/2016
3	Glycemic Control 05/2015 - 04/2003
2	Critical Care (Surgical Intensive Care) 01/2022 - 02/2007